Since the publication of the Osteoporosis Canada guide-lines in 2002, there has been a
paradigm shift in the prevention and treatment of osteoporosis and fractures. 1, 2 The focus now …

The endoplasmic reticulum ( ER ) is a membranous intracellular organelle and the first
compartment of the secretory pathway. As such, the ER contributes to the production and folding …

Background: Fractures have largely been assessed by their impact on quality of life or health
care costs. We conducted this study to evaluate the relation between fractures and mortality…

Background Depression and osteoporotic fractures are common ailments among elderly
persons. Selective serotonin reuptake inhibitors (SSRIs) are frequently used in the treatment of …

Teriparatide (rDNA origin) injection [recombinant human PTH (1–34)] stimulates bone formation,
increases bone mineral density (BMD), and restores bone architecture and integrity. In …

Context Hip fractures are a public health concern because they are associated with
significant morbidity, excess mortality, and the majority of the costs directly attributable to …

We reviewed the epidemiology, diagnosis, and treatment of vertebral fractures due to
osteoporosis in the elderly. Vertebral fractures are underdiagnosed despite their high prevalence …

A. Abstract Objective: To review the effect of risedronate on bone density and fractures in
postmenopausal women. Data Sources: We searched MEDLINE from 1966 to the end of 2000 …

Background. Vitamin B 12 deficiency is common, increasing with age. Most people are
treated in primary care with intramuscular vitamin B 12 . Several studies have reported equal …

Glucocorticoids are widely used to treat several diseases; however, one of their major
consequences is a deleterious effect on bone that may lead to glucocorticoid-induced osteoporosis…