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A 72-year-old man with a 15-year history of diabetes mellitus presented with an asymptomatic, whitish-yellow plaque on the sole of his right foot. The lesion measured 7 cm × 4.5 cm and had a verrucous surface and a peripheral hyperkeratotic collarette.
Figure 1: Histopathologic findings of carcinoma cuniculatum. Note the presence of hyperkeratosis, parakeratosis, acanthosis and nests of well-differentiated squamous epithelium with slight atypia extending into the dermis. The lesion was surrounded by chronic inflammatory cells.