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Figures
Figure 1: Two designs of randomized controlled trials used to investigate long-term antidepressant therapy.
Figure 2: Flow diagram for identification of classic placebo-controlled randomized controlled trials.
Figure 3: Pooled analysis of response to treatment (50% improvement in depression score relative to baseline) in 6 classic randomized controlled trials of selective serotonin reuptake inhibitors in patients with major depression. The vertical line represents no difference between compared treatments.
Figure 4: Pooled analysis of remission (score of 7 or below on the Hamilton rating scale for depression) in 4 classic randomized controlled trials of selective serotonin reuptake inhibitors in patients with major depression. The vertical line represents no difference between compared treatments.
Figure 5: Pooled analysis of overall acceptability (total dropouts) in 6 classic randomized controlled trials of selective serotonin reuptake inhibitors in patients with major depression. The vertical line represents no difference between compared treatments.