Article Figures & Tables
Figures
Figure 1: Flow chart for selection of systematic reviews included in the overview of systematic reviews of biologics for treatment of rheumatoid arthritis.
Figure 2: Comparison of each biologic to placebo for benefit (defined as a 50% improvement in patient- and physician-reported criteria of the American College of Rheumatology [ACR50]). A value greater than 1.0 indicates a benefit from the biologic. CI = confidence interval. For details of studies included for each biologic, refer to Appendix 2 (avaiable at www.cmaj.ca/cgi/content/full/cmaj.091391/DC1).
Figure 3: Comparison of each biologic to placebo for safety (deterined by number of withdrawals because of adverse events). A value less than 1.0 indicates a benefit from the biologic. CI = confidence interval. For details of the studies included for each biologic, refer to Appendix 2 (avaiable at www.cmaj.ca/cgi/content/full/cmaj.091391/DC1).
Figure 4: Indirect comparison of each biologic to each other for benefit (ACR50). A value greater than 1.0 indicate a benefit from the biologic. CI = confidence interval. I2 values for the studies are presented in Figure 2.
Figure 5: Indirect comparison of biologics to each other for safety (determined by number of withdrawals because of adverse events). A value greater than 1.0 indicate a benefit from the biologic. CI = confidence interval. I2 values for the studies are presented in Figure 2.