Research
Persistence of bactericidal antibodies following early infant vaccination with a serogroup B meningococcal vaccine and immunogenicity of a preschool booster dose
Matthew D. Snape, Praveen Saroey, Tessa M. John, Hannah Robinson, Sarah Kelly, Nicoletta Gossger, Ly-Mee Yu, Huajun Wang, Daniela Toneatto, Peter M. Dull and Andrew J. Pollard
CMAJ October 15, 2013 185 (15) E715-E724; DOI: https://doi.org/10.1503/cmaj.130257
Matthew D. Snape
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
MBBS MDPraveen Saroey
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
MBBSTessa M. John
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
BSc(Hons)Hannah Robinson
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
DipHESarah Kelly
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
MScNicoletta Gossger
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
MDLy-Mee Yu
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
MScHuajun Wang
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
MScDaniela Toneatto
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
MDPeter M. Dull
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
MDAndrew J. Pollard
Department of Paediatrics (Snape, Saroey, John, Robinson, Kelly, Gossger, Pollard), University of Oxford and NIHR (National Institute for Health Research) Oxford Biomedical Research Centre, Oxford, UK; Centre for Statistics in Medicine (Yu), University of Oxford, Oxford, UK; Novartis Vaccines and Diagnostics (Wang, Toneatto, Dull), Siena, Italy
MBBS PhD![Loading Loading](https://www.cmaj.ca/sites/all/modules/contrib/panels_ajax_tab/images/loading.gif)
Data supplements
Online Appendices
- Appendix 1: Reverse cumulative distribution curves for hSBA titres at baseline and following the first dose of vaccine
- Appendix 2: hSBA geometric mean titres for all visits in the original study and follow-up study
- Appendix 3: Local reactogenicity following administration of 4CMenB (3a) and rMenB (3b).
- Appendix 4: Systemic reactogenicity of 4CMenB (4a) and rMenB (4b).
Related Articles
- (2013). Highlights. CMAJ, 185(15), 1295. Accessed August 07, 2024. Retrieved from http://www.cmaj.ca/content/185/15/1295.
In this issue
Article tools
Respond to this article
Persistence of bactericidal antibodies following early infant vaccination with a serogroup B meningococcal vaccine and immunogenicity of a preschool booster dose
Matthew D. Snape, Praveen Saroey, Tessa M. John, Hannah Robinson, Sarah Kelly, Nicoletta Gossger, Ly-Mee Yu, Huajun Wang, Daniela Toneatto, Peter M. Dull, Andrew J. Pollard
CMAJ Oct 2013, 185 (15) E715-E724; DOI: 10.1503/cmaj.130257
Persistence of bactericidal antibodies following early infant vaccination with a serogroup B meningococcal vaccine and immunogenicity of a preschool booster dose
Matthew D. Snape, Praveen Saroey, Tessa M. John, Hannah Robinson, Sarah Kelly, Nicoletta Gossger, Ly-Mee Yu, Huajun Wang, Daniela Toneatto, Peter M. Dull, Andrew J. Pollard
CMAJ Oct 2013, 185 (15) E715-E724; DOI: 10.1503/cmaj.130257