Data supplements
Online Video Appendices (no sound)
Appendix 1 (no sound)
Bubble echocardiogram showing bubbles filling the left atrium and ventricle within 3 cardiac cycles, suggesting right-to-left intracardiac shunting.
Appendix 2 (no sound)
The patient has undergone Amplatzer septal occluder implantation for closure of a patent foramen ovale. A follow-up cardiac echocardiogram showed no residual shunting flow.