Backfilled | 442 (8.9) | 0 | 0 | 32 (1.3) | 509 (50.8) | 509 (63.5) |
Age at index date, yr, mean ± SD | 35.3 ± 11.8 | 35.6 ± 11.9 | 35.5 ± 10.8 | 35.6 ± 10.8 | 37.5 ± 11.3 | 37.7 ± 11.2 |
Age at index date, yr, median (IQR) | 34 (27–43) | 34 (27–44) | 34 (27–43) | 35 (27–43) | 37 (28–46) | 38 (28–46) |
Age at index date, yr | | | | | | |
0–24 | 926 (18.7) | 777 (18.9) | 427 (17.2) | 404 (17.0) | 139 (13.9) | 104 (13.0) |
25–29 | 828 (16.7) | 669 (16.2) | 429 (17.3) | 413 (17.4) | 149 (14.9) | 124 (15.5) |
30–34 | 766 (15.4) | 623 (15.1) | 395 (15.9) | 370 (15.6) | 141 (14.1) | 109 (13.6) |
35–39 | 720 (14.5) | 566 (13.7) | 348 (14.0) | 331 (13.9) | 136 (13.6) | 102 (12.7) |
40–44 | 640 (12.9) | 533 (12.9) | 350 (14.1) | 339 (14.3) | 153 (15.3) | 121 (15.1) |
45–49 | 464 (9.4) | 407 (9.9) | 250 (10.1) | 246 (10.4) | 129 (12.9) | 114 (14.2) |
50–54 | 305 (6.1) | 265 (6.4) | 154 (6.2) | 148 (6.2) | 76 (7.6) | 66 (8.2) |
≥ 55 | 313 (6.3) | 278 (6.8) | 127 (5.1) | 123 (5.2) | 79 (7.9) | 61 (7.6) |
Birth cohort | | | | | | |
< 1945 | 34 (0.7) | 28 (0.7) | 15 (0.6) | 14 (0.6) | 9 (0.9) | 6 (0.7) |
1945–1964 | 1157 (23.3) | 1002 (24.3) | 611 (24.6) | 600 (25.3) | 347 (34.6) | 289 (36.1) |
1965–1975 | 1213 (24.4) | 1004 (24.4) | 632 (25.5) | 612 (25.8) | 260 (25.9) | 208 (26.0) |
> 1975 | 2558 (51.6) | 2084 (50.6) | 1222 (49.3) | 1148 (48.4) | 386 (38.5) | 298 (37.2) |
Sex | | | | | | |
Female | 2348 (47.3) | 1974 (47.9) | 1054 (42.5) | 997 (42.0) | 444 (44.3) | 370 (46.2) |
Male | 2614 (52.7) | 2144 (52.1) | 1426 (57.5) | 1377 (58.0) | 558 (55.7) | 431 (53.8) |
Urbanicity at index date | | | | | | |
Missing or unknown | 53 (1.1) | 32 (0.8) | 19 (0.8) | 18 (0.8) | 6 (0.6) | ≤ 5 |
Urban | 3244 (65.4) | 2632 (63.9) | 1662 (67.0) | 1598 (67.3) | 734 (73.3) | 579 (72.3) |
Rural | 1665 (33.6) | 1454 (35.3) | 799 (32.2) | 758 (31.9) | 262 (26.1) | ≤ 221 |
Community status at index date§ | | | | | | |
Missing or unknown | 281 (5.7) | 227 (5.5) | 157 (6.3) | 155 (6.5) | 83 (8.3) | 65 (8.1) |
Outside of First Nations community | 3583 (72.2) | 2920 (70.9) | 1795 (72.4) | 1718 (72.4) | 750 (74.9) | 586 (73.2) |
Within First Nations community | 1098 (22.1) | 971 (23.6) | 528 (21.3) | 501 (21.1) | 169 (16.9) | 150 (18.7) |
LHIN at index date | | | | | | |
Missing or unknown | 30 (0.6) | 16 (0.4) | 11 (0.4) | 11 (0.5) | ≤ 5 | ≤ 5 |
1. Erie St. Clair | 328 (6.6) | 249 (6.0) | 148 (6.0) | 139 (5.9) | ≤ 5 | 35 (4.4) |
2. South West | 376 (7.6) | 310 (7.5) | 185 (7.5) | 174 (7.3) | 80 (8.0) | 65 (8.1) |
3. Waterloo Wellington | 56 (1.1) | 50 (1.2) | 29 (1.2) | 27 (1.1) | 15 (1.5) | 12 (1.5) |
4. Hamilton Niagara Haldimand Brant | 474 (9.6) | 387 (9.4) | 238 (9.6) | 229 (9.6) | 98 (9.8) | 81 (10.1) |
5. Central West | 33 (0.7) | 28 (0.7) | 15 (0.6) | 14 (0.6) | 9 (0.9) | 7 (0.9) |
6. Mississauga Halton | 28 (0.6) | 22 (0.5) | 12 (0.5) | 10 (0.4) | ≤ 5 | ≤ 5 |
7. Toronto Central | 335 (6.8) | 271 (6.6) | 167 (6.7) | 163 (6.9) | 88 (8.8) | 66 (8.2) |
8. Central | 55 (1.1) | 50 (1.2) | 27 (1.1) | 27 (1.1) | 13 (1.3) | 11 (1.4) |
9. Central East | 138 (2.8) | 110 (2.7) | 69 (2.8) | 68 (2.9) | 40 (4.0) | 32 (4.0) |
10. South East | 108 (2.2) | 88 (2.1) | 57 (2.3) | 56 (2.4) | 31 (3.1) | 25 (3.1) |
11. Champlain | 184 (3.7) | 142 (3.4) | 95 (3.8) | 91 (3.8) | 32 (3.2) | 23 (2.9) |
12. North Simcoe Muskoka | 106 (2.1) | 82 (2.0) | 52 (2.1) | 48 (2.0) | 29 (2.9) | 23 (2.9) |
13. North East | 1023 (20.6) | 845 (20.5) | 530 (21.4) | 509 (21.4) | 202 (20.2) | 151 (18.9) |
14. North West | 1688 (34.0) | 1468 (35.6) | 845 (34.1) | 808 (34.0) | 310 (30.9) | 267 (33.3) |
Comorbidities¶ | | | | | | |
ADG score 1 year before index date, mean ± SD | 5.1 ± 3.8 | 5.1 ± 3.7 | 5.1 ± 3.7 | 5.1 ± 3.7 | 5.2 ± 3.7 | 5.1 ± 3.6 |
ADG score 1 year before index date, median (IQR) | 4 (2–8) | 4 (2–8) | 5 (2–8) | 5 (2–8) | 5 (2–8) | 5 (2–7) |
Number of ADG categories 1 year before index date | | | | | | |
0 | 387 (7.7) | 323 (7.8) | 200 (8.1) | 193 (8.1) | 81 (8.1) | 65 (8.1) |
1–4 | 2100 (42.3) | 1759 (42.7) | 1023 (41.3) | 974 (41.0) | 393 (39.2) | 314 (39.2) |
5–9 | 1806 (36.4) | 1500 (36.4) | 945 (38.1) | 908 (38.2) | 399 (39.8) | 325 (40.6) |
≥ 10 | 674 (13.6) | 536 (13.0) | 312 (12.6) | 299 (12.5) | 129 (12.9) | 97 (12.1) |
Mental health records | | | | | | |
Substance use and addictive disorders | | | | | | |
Before index date | 3728 (75.1) | 3069 (74.5) | 1918 (77.3) | 1825 (76.9) | 743 (74.2) | 567 (70.8) |
Before Dec. 31, 2018 | 4233 (85.3) | 3500 (85.0) | 2189 (88.3) | 2094 (88.2) | 858 (85.6) | 667 (83.3) |
Mood disorders | | | | | | |
Before index date | 1890 (38.1) | 1559 (37.9) | 931 (37.5) | 891 (37.5) | 365 (36.4) | 281 (35.1) |
Before Dec. 31, 2018 | 2566 (51.7) | 2138 (51.9) | 1303 (52.5) | 1254 (52.8) | 539 (53.8) | 425 (53.1) |
Personality disorders | | | | | | |
Before index date | 821 (16.5) | 663 (16.1) | 428 (17.3) | 408 (17.2) | 163 (16.3) | 121 (15.1) |
Before Dec. 31, 2018 | 1099 (22.1) | 897 (21.8) | 599 (24.2) | 574 (24.2) | 232 (23.2) | 181 (22.6) |
Schizophrenia spectrum and other psychotic disorders | | | | | | |
Before index date | 619 (12.5) | 494 (12.0) | 331 (13.3) | 314 (13.2) | 123 (12.3) | 83 (10.4) |
Before Dec. 31, 2018 | 992 (20.0) | 809 (19.6) | 551 (22.2) | 531 (22.4) | 213 (21.3) | 152 (19.0) |
Anxiety disorders | | | | | | |
Before index date | 3731 (75.2) | 3107 (75.4) | 1914 (77.2) | 1833 (77.2) | 796 (79.4) | 621 (77.5) |
Before Dec. 31, 2018 | 4144 (83.5) | 3447 (83.7) | 2121 (85.5) | 2035 (85.7) | 875 (87.3) | 691 (86.3) |
Trauma or stressor-related disorders | | | | | | |
Before index date | 1343 (27.1) | 1122 (27.2) | 712 (28.7) | 685 (28.9) | 257 (25.6) | 198 (24.7) |
Before Dec. 31, 2018 | 1849 (37.3) | 1545 (37.5) | 1000 (40.3) | 969 (40.8) | 379 (37.8) | 297 (37.1) |
Deliberate self harm | | | | | | |
Before index date | 836 (16.8) | 675 (16.4) | 436 (17.6) | 411 (17.3) | 152 (15.2) | 113 (14.1) |
Before Dec. 31, 2018 | 1245 (25.1) | 1025 (24.9) | 677 (27.3) | 644 (27.1) | 236 (23.6) | 179 (22.3) |
Disease-specific records | | | | | | |
Genotype of HCV infection | | | | | | |
Genotype 1 | 1711 (34.5) | 1711 (41.5) | 1592 (64.2) | 1592 (67.1) | 665 (66.4) | 533 (66.5) |
Genotype 2 | 162 (3.3) | 162 (3.9) | 149 (6.0) | 149 (6.3) | 70 (7.0) | 62 (7.7) |
Genotype 3 | 600 (12.1) | 600 (14.6) | 559 (22.5) | 559 (23.5) | 217 (21.7) | 164 (20.5) |
Genotype 4 | ≤ 5 | ≤ 5 | ≤ 5 | ≤ 5 | ≤ 5 | ≤ 5 |
Multiple genotypes | ≤ 19 | ≤ 19 | ≤ 16 | ≤ 16 | ≤ 6 | ≤ 5 |
Missing or unknown** | 2469 (49.8) | 1625 (39.5) | 163 (6.6) | 57 (2.4) | 43 (4.3) | 36 (4.5) |
HBV | | | | | | |
Before index date | 52 (1.0) | 42 (1.0) | 26 (1.0) | 26 (1.1) | 14 (1.4) | 13 (1.6) |
Before Dec. 31, 2018 | 119 (2.4) | 103 (2.5) | 64 (2.6) | 64 (2.7) | 32 (3.2) | 27 (3.4) |
HIV | | | | | | |
Before index date | 94 (1.9) | 89 (2.2) | 45 (1.8) | 45 (1.9) | 29 (2.9) | 22 (2.7) |
Before Dec. 31, 2018 | 187 (3.8) | 178 (4.3) | 110 (4.4) | 109 (4.6) | 47 (4.7) | 32 (4.0) |
Cirrhosis | | | | | | |
Before index date | 89 (1.8) | 79 (1.9) | 50 (2.0) | 50 (2.1) | 33 (3.3) | 31 (3.9) |
Before Dec. 31, 2018 | 240 (4.8) | 224 (5.4) | 173 (7.0) | 173 (7.3) | 119 (11.9) | 105 (13.1) |
Decompensated cirrhosis | | | | | | |
Before index date | 65 (1.3) | 58 (1.4) | 36 (1.5) | 36 (1.5) | 24 (2.4) | 22 (2.7) |
Before Dec. 31, 2018 | 139 (2.8) | 130 (3.2) | 96 (3.9) | 96 (4.0) | 67 (6.7) | 59 (7.4) |
Hepatocellular carcinoma | | | | | | |
Before index date | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Before Dec. 31, 2018 | 15 (0.3) | 14 (0.3) | 14 (0.6) | 14 (0.6) | 9 (0.9) | 9 (1.1) |
Liver transplant | | | | | | |
Before index date | ≤ 5 | ≤ 5 | ≤ 5 | ≤ 5 | 0 (0.0) | 0 (0.0) |
Before Dec. 31, 2018 | 18 (0.4) | 18 (0.4) | 12 (0.5) | 12 (0.5) | 10 (1.0) | 9 (1.1) |