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Parechovirus infections in infants
Maude Paquette, Christian Renaud and Jesse Papenburg
CMAJ January 23, 2023 195 (3) E121; DOI: https://doi.org/10.1503/cmaj.221360
Maude Paquette
Division of Infectious Diseases, Department of Pediatrics (Paquette, Renaud), Centre Hospitalier Universitaire Sainte-Justine; Division of Microbiology, Department of Clinical Laboratory Medicine (Paquette, Renaud), Optilab Montreal — Centre Hospitalier Universitaire Sainte-Justine; Division of Pediatric Infectious Diseases, Department of Pediatrics (Papenburg), Montreal Children’s Hospital, McGill University Health Centre; Division of Microbiology, Department of Clinical Laboratory Medicine (Papenburg), Optilab Montreal — McGill University Health Centre, Montréal, Que.
MDChristian Renaud
Division of Infectious Diseases, Department of Pediatrics (Paquette, Renaud), Centre Hospitalier Universitaire Sainte-Justine; Division of Microbiology, Department of Clinical Laboratory Medicine (Paquette, Renaud), Optilab Montreal — Centre Hospitalier Universitaire Sainte-Justine; Division of Pediatric Infectious Diseases, Department of Pediatrics (Papenburg), Montreal Children’s Hospital, McGill University Health Centre; Division of Microbiology, Department of Clinical Laboratory Medicine (Papenburg), Optilab Montreal — McGill University Health Centre, Montréal, Que.
MD MScJesse Papenburg
Division of Infectious Diseases, Department of Pediatrics (Paquette, Renaud), Centre Hospitalier Universitaire Sainte-Justine; Division of Microbiology, Department of Clinical Laboratory Medicine (Paquette, Renaud), Optilab Montreal — Centre Hospitalier Universitaire Sainte-Justine; Division of Pediatric Infectious Diseases, Department of Pediatrics (Papenburg), Montreal Children’s Hospital, McGill University Health Centre; Division of Microbiology, Department of Clinical Laboratory Medicine (Papenburg), Optilab Montreal — McGill University Health Centre, Montréal, Que.
MD MScIn this issue
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Parechovirus infections in infants
Maude Paquette, Christian Renaud, Jesse Papenburg
CMAJ Jan 2023, 195 (3) E121; DOI: 10.1503/cmaj.221360
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- Severe parechovirus infections are mostly caused by genotype PeV-A3
- Infants younger than 3 months are at greatest risk of severe disease3
- Normal cerebrospinal fluid (CSF) parameters do not exclude CNS infection
- Infection of the CNS is associated with cerebral white matter diffusion abnormalities on magnetic resonance imaging (MRI)3
- In infants with CNS infection, long-term neurodevelopmental follow-up is advisable4
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