Article Figures & Tables
Tables
Category Description T — Primary tumour T1 Tumour ≤ 7 cm in greatest dimension, limited to the kidney T1a Tumour ≤ 4 cm T1b Tumour > 4 cm but ≤ 7 cm T2 Tumour > 7 cm in greatest dimension, limited to the kidney T2a Tumour > 7 cm but ≤ 10 cm T2b Tumour > 10 cm but limited to the kidney T3 Tumour extends into major veins or perinephric tissues but not into ipsilateral adrenal gland and not beyond the Gerota fascia T3a Tumour extends into the renal vein or its segmental branches, or invades the pelvicalyceal system, or perirenal or renal sinus fat T3b Tumour grossly extends into the vena cava below the diaphragm T3c Tumour grossly extends into the vena cave above the diaphragm or the wall of the vena cava T4 Tumour invades beyond the Gerota fascia (including contiguous extension into the ipsilateral adrenal gland) N — Regional lymph nodes N0 No regional lymph node metastasis N1 Metastasis in regional lymph node(s) M — Distant metastasis M0 No distant metastasis M1 Distant metastasis TNM stage grouping Stage I T1 N0 M0 Stage II T2 N0 M0 Stage III T3 N0 M0 T1, T2, or T3 N1 M0 Stage IV T4 Any N M0 Any T Any N M1 Note: TNM = tumour, node, metastasis.
- Table 2:
International Metastatic RCC Database Consortium risk stratification criteria for metastatic disease (8)
IMDC criteria Hemoglobin < LLN
Platelets > ULN
Neutrophil count > ULN
Corrected calcium > ULN
Karnofsky Performance Scale score < 80%
Time from diagnosis to systemic treatment < 1 year
IMDC risk group Score Favourable risk 0 Intermediate risk 1–2 Poor risk 3–6 Note: IMDC = International Metastatic RCC Database Consortium, LLN = lower limit of normal, RCC = renal cell carcinoma, ULN = upper limit of normal.