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Angiotensin-converting-enzyme inhibitor–induced angioedema
Danica Quickfall, Baruch Jakubovic and Jonathan S. Zipursky
CMAJ May 17, 2021 193 (20) E735; DOI: https://doi.org/10.1503/cmaj.202308
Danica Quickfall
Department of Medicine (Quickfall, Zipursky), University of Toronto; Department of Medicine (Jakubovic, Zipursky), Sunnybrook Health Sciences Centre; Division of Clinical Pharmacology and Toxicology, Department of Medicine (Zipursky), University of Toronto; Institute of Health Policy, Management, and Evaluation (Zipursky), University of Toronto, Toronto, Ont.
MDCMBaruch Jakubovic
Department of Medicine (Quickfall, Zipursky), University of Toronto; Department of Medicine (Jakubovic, Zipursky), Sunnybrook Health Sciences Centre; Division of Clinical Pharmacology and Toxicology, Department of Medicine (Zipursky), University of Toronto; Institute of Health Policy, Management, and Evaluation (Zipursky), University of Toronto, Toronto, Ont.
MDJonathan S. Zipursky
Department of Medicine (Quickfall, Zipursky), University of Toronto; Department of Medicine (Jakubovic, Zipursky), Sunnybrook Health Sciences Centre; Division of Clinical Pharmacology and Toxicology, Department of Medicine (Zipursky), University of Toronto; Institute of Health Policy, Management, and Evaluation (Zipursky), University of Toronto, Toronto, Ont.
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- Quickfall, D., Jakubovic, B., & Zipursky, J. S. (2021). Angioœdème causé par l’inhibiteur de l’enzyme de conversion de l’angiotensine. CMAJ, 193(31), E1227-E1228. Accessed August 17, 2024. https://doi.org/10.1503/cmaj.202308-f.
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Angiotensin-converting-enzyme inhibitor–induced angioedema
Danica Quickfall, Baruch Jakubovic, Jonathan S. Zipursky
CMAJ May 2021, 193 (20) E735; DOI: 10.1503/cmaj.202308
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- Angiotensin-converting-enzyme (ACE) inhibitors are the leading cause of drug-induced angioedema
- Common symptoms include facial, lip, tongue and upper airway swelling
- Airway compromise is a life-threatening consequence of ACE inhibitor–induced angioedema
- Stopping the ACE inhibitor is the most important treatment
- Angiotensin receptor blockers can be used if there is a clinical indication for renin–angiotensin–aldosterone system blockade
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