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Ketamine for the treatment of acute pain
William K. Silverstein, David N. Juurlink and Jonathan S. Zipursky
CMAJ November 01, 2021 193 (43) E1663; DOI: https://doi.org/10.1503/cmaj.210878
William K. Silverstein
Department of Medicine (Silverstein, Juurlink, Zipursky), University of Toronto; Division of Clinical Pharmacology and Toxicology (Juurlink, Zipursky), Sunnybrook Health Sciences Centre; Institute of Health Policy, Management, and Evaluation (Juurlink, Zipursky), University of Toronto; ICES Central (Juurlink), Toronto, Ont.
MDDavid N. Juurlink
Department of Medicine (Silverstein, Juurlink, Zipursky), University of Toronto; Division of Clinical Pharmacology and Toxicology (Juurlink, Zipursky), Sunnybrook Health Sciences Centre; Institute of Health Policy, Management, and Evaluation (Juurlink, Zipursky), University of Toronto; ICES Central (Juurlink), Toronto, Ont.
MD PhDJonathan S. Zipursky
Department of Medicine (Silverstein, Juurlink, Zipursky), University of Toronto; Division of Clinical Pharmacology and Toxicology (Juurlink, Zipursky), Sunnybrook Health Sciences Centre; Institute of Health Policy, Management, and Evaluation (Juurlink, Zipursky), University of Toronto; ICES Central (Juurlink), Toronto, Ont.
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Ketamine for the treatment of acute pain
William K. Silverstein, David N. Juurlink, Jonathan S. Zipursky
CMAJ Nov 2021, 193 (43) E1663; DOI: 10.1503/cmaj.210878
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- Article
- Ketamine’s analgesic and anesthetic effects are dose dependent
- Ketamine is an effective analgesic at subanesthetic doses
- Low-dose ketamine is safe
- Clinicians should assess for contraindications before starting treatment
- Use of ketamine for the treatment of acute pain can have opioid-sparing effects
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