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Ketamine for the treatment of acute pain
William K. Silverstein, David N. Juurlink and Jonathan S. Zipursky
CMAJ November 01, 2021 193 (43) E1663; DOI: https://doi.org/10.1503/cmaj.210878
William K. Silverstein
Department of Medicine (Silverstein, Juurlink, Zipursky), University of Toronto; Division of Clinical Pharmacology and Toxicology (Juurlink, Zipursky), Sunnybrook Health Sciences Centre; Institute of Health Policy, Management, and Evaluation (Juurlink, Zipursky), University of Toronto; ICES Central (Juurlink), Toronto, Ont.
MDDavid N. Juurlink
Department of Medicine (Silverstein, Juurlink, Zipursky), University of Toronto; Division of Clinical Pharmacology and Toxicology (Juurlink, Zipursky), Sunnybrook Health Sciences Centre; Institute of Health Policy, Management, and Evaluation (Juurlink, Zipursky), University of Toronto; ICES Central (Juurlink), Toronto, Ont.
MD PhDJonathan S. Zipursky
Department of Medicine (Silverstein, Juurlink, Zipursky), University of Toronto; Division of Clinical Pharmacology and Toxicology (Juurlink, Zipursky), Sunnybrook Health Sciences Centre; Institute of Health Policy, Management, and Evaluation (Juurlink, Zipursky), University of Toronto; ICES Central (Juurlink), Toronto, Ont.
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- Yuhalogarasan, A., Barclay, C., & Verbeek, P. R. (2022). Low-dose ketamine in the prehospital setting. CMAJ, 194(5), E171. Accessed July 12, 2024. https://doi.org/10.1503/cmaj.80599.
- Silverstein, W. K., Juurlink, D. N., & Zipursky, J. S. (2022). Kétamine pour le traitement de la douleur aiguë. CMAJ, 194(5), E179-E180. Accessed July 12, 2024. https://doi.org/10.1503/cmaj.210878-f.
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Ketamine for the treatment of acute pain
William K. Silverstein, David N. Juurlink, Jonathan S. Zipursky
CMAJ Nov 2021, 193 (43) E1663; DOI: 10.1503/cmaj.210878
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- Article
- Ketamine’s analgesic and anesthetic effects are dose dependent
- Ketamine is an effective analgesic at subanesthetic doses
- Low-dose ketamine is safe
- Clinicians should assess for contraindications before starting treatment
- Use of ketamine for the treatment of acute pain can have opioid-sparing effects
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